ARP Rheumatology
ARP Rheumatology
+

Online first

ARP Rheumatology - Online first: 2022-03-27
Letter

A rare case of cerebellar degeneration due to Primary Sjogren’s Syndrome (PSS)

Authors

Aveiro M, Cunha R, Rodrigues T, Domingues J, Aguiar R, Oliveira A

Abstract

Sjogren's syndrome (SS) is an autoimmune pathology which mainly affects salivary and lacrimal glands. Cerebellar degeneration association with SS is very rare, with only a few cases described. The treatment of SS with central nervous system involvement is not consensual. We present a 48-year-old woman with dysarthria, diplopia and ataxia associated with xerostomia. The brain magnetic imaging revealed bilateral cerebellar atrophy. She had antibody positivity for anti-SSA and anti-SSB and minor salivary glands biopsy revealed lymphocytic infiltration. Methylprednisolone, cyclophosphamide and intravenous immunoglobulin yielded no results. Rituximab was initiated with improvement in dysarthria and coordination.

Share

 

Publication:

2022-03-27

Cite:

Marcelo Aveiro, Rita Cunha, Tatiana Rodrigues, Joana Domingues, Renata Aguiar, Ana Oliveira. A rare case of cerebellar degeneration due to Primary Sjogren’s Syndrome (PSS). ARP Rheumatology, 2022, online-first - http://www.arprheumatology.com/article_abstract.php?id=1423
Copy citation